O-011. Prevention of threatening ovarian hyperstimulation by coasting

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Coasting (withholding gonadotrophins) for preventing ovarian hyperstimulation syndrome.

BACKGROUND Ovarian hyperstimulation syndrome (OHSS) is an iatrogenic and potentially life threatening condition resulting from excessive ovarian stimulation. Reported incidence varies from 1% to 10% of in vitro fertilization (IVF) cycles. The factors contributing to OHSS have not been completely explained. The release of vasoactive substances secreted by the ovaries under human chorionic gonado...

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Effect of late coasting used in the prevention of ovarian hyperstimulation syndrome on oocyte quality

Objective: To detect the effect of late coasting on oocyte quality. Design: Retrospective study. Setting: Samir Abbas Medical Center Materials and methods: Patients where estradiol level was over 4000 pg/ml and late coasting was used as a method to prevent OHSS, and patients where estradiol level was over 4000 pg / ml but no coasting was done Main outcome measure(s) : Oocyte quality. Results: n...

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Criteria of a successful coasting protocol for the prevention of severe ovarian hyperstimulation syndrome.

BACKGROUND The aim of this study is to report a large series of patients (n = 1223) at risk of developing ovarian hyperstimulation syndrome (OHSS) who underwent coasting. METHODS Coasting started when the leading follicle reached 16 mm and continued until the estradiol (E2) level fell to 3000 pg/ml. RESULTS The E2 level at the start of coasting was (mean +/ SD) 6408 +/- 446 and it fell to 2...

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Cabergoline versus Coasting in the Prevention of Ovarian Hyperstimulation Syndrome and Assisted Reproductive Technologies Outcome in High Risk Patients

Background Coasting is the most common method used in the prevention of ovarian hyperstimulation syndrome (OHSS) acting through vascular endothelial growth factor (VEGF) reduction. However, the pregnancy rate is reported to fall with coasting when it takes more than three days. Recently lowdose cabergoline, a selective D2 dopamine receptor agonist has been proven to selectively reduce vascular ...

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Prevention of Ovarian Hyperstimulation Syndrome

Ovarian hyperstimulation syndrome (OHSS) is rare but most serious complication of ovarian stimulation. Symptoms are mainly related to increased capillary permeability leading to extravasation of fluid into extravascular compartment. Disease pathophysiology is linked to hCG (human chorionic gonadotropin) which acts through angiogenic molecule vascular endothelial growth factor (VEGF). There is r...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 1997

ISSN: 1460-2350,0268-1161

DOI: 10.1093/humrep/12.suppl_2.5